O Carter Snead Selected Research

Vigabatrin

11/2020	Retinal defect in children with infantile spasms of varying etiologies: An observational study.
8/2015	Vigabatrin as First-Line Treatment for Infantile Spasms Not Related to Tuberous Sclerosis Complex.
4/2015	Adrenocorticotropic hormone versus prednisolone in the treatment of infantile spasms post vigabatrin failure.
12/2014	Vigabatrin retinal toxicity in children with infantile spasms: An observational cohort study.
7/2010	Vigabatrin-associated reversible MRI signal changes in patients with infantile spasms.
8/2007	Contrast sensitivity is reduced in children with infantile spasms.
2/2005	Reduced visual function associated with infantile spasms in children on vigabatrin therapy.
7/2002	Therapeutic intervention in mice deficient for succinate semialdehyde dehydrogenase (gamma-hydroxybutyric aciduria).
1/2002	Treatment of infantile spasms: an evidence-based approach.

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O Carter Snead Research Topics

Disease

38	Seizures (Absence Seizure) 01/2020 - 09/2001
29	Epilepsy (Aura) 01/2022 - 06/2002
21	Drug Resistant Epilepsy 10/2022 - 08/2003
14	succinic semialdehyde dehydrogenase deficiency 03/2009 - 07/2002
12	Infantile Spasms (West Syndrome) 11/2020 - 01/2002
8	Partial Epilepsies (Epilepsy, Partial) 10/2022 - 05/2003
7	Tuberous Sclerosis (Bourneville's Disease) 11/2016 - 01/2002
6	Spasm (Spasms) 01/2018 - 02/2007
3	Lennox Gastaut Syndrome 01/2015 - 08/2003
3	Absence Epilepsy (Childhood Absence Epilepsy) 08/2012 - 11/2004
3	Cognitive Dysfunction 11/2009 - 07/2006
3	Status Epilepticus (Complex Partial Status Epilepticus) 04/2007 - 01/2006
3	Alcoholism (Alcohol Abuse) 03/2006 - 01/2003
3	Malformations of Cortical Development 11/2004 - 05/2002
2	Brain Diseases (Brain Disorder) 01/2019 - 05/2015
2	Ataxia (Dyssynergia) 03/2009 - 04/2008
2	Hyperkinesis 12/2006 - 10/2003
2	Narcolepsy 03/2006 - 01/2004
1	Infantile Epileptic-Dyskinetic Encephalopathy 01/2019
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 09/2018
1	Memory Disorders (Memory Loss) 01/2018
1	Rett Syndrome (Rett's Disorder) 01/2018
1	Neurodevelopmental Disorders 01/2018
1	Pyridoxine-dependent epilepsy 05/2015
1	Methylenetetrahydrofolate reductase deficiency 05/2015
1	Menkes Kinky Hair Syndrome (Menkes Disease) 05/2015
1	Pyruvate Dehydrogenase Complex Deficiency Disease 05/2015
1	Nonketotic Hyperglycinemia 05/2015
1	Bipolar Disorder (Manic Depressive Psychosis) 11/2011
1	Mania (Manias) 11/2011
1	Hydrocephalus (Hydrocephaly) 12/2010

Drug/Important Bio-Agent (IBA)

14	gamma-Aminobutyric Acid (GABA)IBA 07/2015 - 01/2003
13	Succinate-Semialdehyde Dehydrogenase (Succinic Semialdehyde Dehydrogenase)IBA 03/2009 - 07/2002
9	Vigabatrin FDA Link 11/2020 - 01/2002
9	Anticonvulsants (Antiepileptic Drugs)IBA 07/2013 - 01/2002
9	trans- 1,4- Bis(2- chlorobenzaminomethyl)cyclohexane DihydrochlorideIBA 08/2012 - 01/2002
6	Pharmaceutical PreparationsIBA 01/2020 - 01/2003
6	trans-sodium crocetinate (crocetin)IBA 11/2016 - 09/2005
6	CholesterolIBA 08/2012 - 01/2002
5	GABA-B ReceptorsIBA 07/2015 - 07/2002
3	Ethosuximide (Zarontin)FDA LinkGeneric 01/2020 - 11/2004
3	4-hydroxybutyric acidIBA 01/2020 - 05/2006
3	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019 - 10/2003
3	Adrenocorticotropic Hormone (ACTH)FDA Link 08/2015 - 01/2002
3	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2015 - 01/2002
3	4-Butyrolactone (gamma Butyrolactone)IBA 05/2009 - 03/2006
3	SteroidsIBA 01/2006 - 01/2002
2	Retinaldehyde (Retinal)IBA 11/2020 - 12/2014
2	ProdrugsIBA 01/2020 - 03/2006
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2019
2	Dopamine (Intropin)FDA LinkGeneric 01/2019 - 10/2003
2	Valproic Acid (Depakote)FDA LinkGeneric 11/2011 - 11/2004
2	Proteins (Proteins, Gene)FDA Link 11/2011 - 04/2009
2	Baclofen FDA LinkGeneric 05/2009 - 01/2008
2	Pentylenetetrazole (Metrazol)IBA 01/2008 - 08/2003
2	Serotonin (5 Hydroxytryptamine)IBA 02/2006 - 10/2003
2	SterolsIBA 11/2004 - 01/2002
2	Hormones (Hormone)IBA 03/2004 - 01/2002
2	BenzodiazepinesIBA 01/2002 - 09/2001
1	neuroligin 2IBA 01/2020
1	NeuroliginsIBA 01/2020
1	Cell Adhesion MoleculesIBA 01/2020
1	Medical MarijuanaIBA 11/2019
1	Carrier Proteins (Binding Protein)IBA 01/2019
1	Qa-SNARE Proteins (Syntaxin)IBA 01/2019
1	OilsIBA 09/2018
1	Plant ExtractsIBA 09/2018
1	Dronabinol (THC)FDA LinkGeneric 09/2018
1	p21-Activated KinasesIBA 01/2018
1	Methyl-CpG-Binding Protein 2IBA 01/2018
1	tertiapinIBA 10/2016
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 11/2015
1	GABA-B Receptor AgonistsIBA 07/2015
1	Aminobutyrates (Aminobutyric Acid)IBA 07/2015
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 05/2015
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 05/2015
1	Oxidoreductases (Dehydrogenase)IBA 05/2015
1	Prednisolone (Predate)FDA LinkGeneric 04/2015
1	N'-geranylpiperazinylfarnesyl acetamideIBA 01/2015
1	Drug CombinationsIBA 07/2013
1	Indicators and Reagents (Reagents)IBA 05/2013
1	Deoxyglucose (2 Deoxy D glucose)IBA 04/2013
1	rostafuroxinIBA 11/2011
1	LithiumIBA 11/2011
1	Adenosine Triphosphatases (ATPase)IBA 11/2011
1	Sodium-Potassium-Exchanging ATPase (Sodium, Potassium ATPase)IBA 11/2011
1	Amobarbital (Amsal)IBA 06/2009
1	GABA Receptors (GABA Receptor)IBA 04/2009

Therapy/Procedure

11	Electrodes (Electrode) 10/2022 - 05/2002
6	Therapeutics 01/2022 - 02/2005
5	Hemispherectomy 08/2017 - 12/2010
4	Ketogenic Diet 10/2014 - 08/2003
3	Implanted Electrodes 10/2022 - 11/2013
3	Vagus Nerve Stimulation 01/2021 - 11/2019
3	Neurosurgical Procedures 12/2011 - 12/2006
2	Long-Term Care 01/2020 - 01/2012
2	Operative Surgical Procedures 12/2010 - 05/2003
1	Anesthesia 01/2019
1	Time-to-Treatment 01/2015
1	Occupational Therapy (Therapy, Occupational) 08/2012